"Smith-Magenis syndrome (SMS) is a chromosomal disorder characterized by a specific pattern of physical, behavioral and developmental features. It is caused by a missing piece of genetic material from chromosome 17, referred to as deletion 17p11.2. The first group of children was described in the 1980's by Ann C.M. Smith, M.A., a genetic counselor, and Ellen Magenis, M.D., a cytogeneticist. Although the exact incidence is not known, it is estimated that SMS occurs in 1 out of 25,000 births. SMS is underdiagnosed, but as awareness of it increases, the number of people identified grows every year."- PRISMS (see below)

Follow these links to learn more about Smith-Magenis Syndrome:

Parents & Researchers Interested in Smith-Magenis Syndrome (PRISMS)

-SMS background, clinical and behavioral features, educational concerns, references and links to genetic counseling services

Online Mendelian Inheritance in Man (OMIM)

-research history, medical references as well as links to other clinical/medical/scientific databases

National Organization for Rare Diseases

-description, alternate link to support group