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Wisconsin Newborn Screening Laboratory: 1998 Statistics

1998 Statistics:

Number of Births 66,027
Number of Samples 68,559

Disorder
Number of Confirmed
Cases in 1998
Prevalence Rate*
PKU 5 1 : 15,531
Galactosemia 1 1 : 58,230
Biotinidase Deficiency 1 1 : 88,467
Congenital Adrenal Hyperplasia 4 1 : 10,000
Congenital Hypothyroidism 22 1 : 3,841
Cystic Fibrosis 13 1 : 4,299
Sickling Disorders
(SS, SC, S-Beta thal)
23 1 : 2971

*Prevalance rates listed are cumulative for all years of screening and include all Wisconsin births.

Causes of Unsatisfactory Samples

All samples are judged for acceptability. Those not acceptable are reported as "Unsatisfactory". The following table lists the most common causes of unsatisfactory samples for the last 3 years

Reason
1997
No. - %
1998
No. - %
1999
No. - %
Blood clots on surface222 - 23%201 - 25%251 - 21%
Incomplete saturation264 - 28%216 - 27%313 - 27%
Filter paper damaged146 - 15%90 - 11%215 - 18%
Blood layered on surface69 - 7%32 - 4%72 - 6%
Blood applied on both sides68 - 7%53 - 7%15 - 1%
Sample delayed by mail108 - 11%45 - 6%44 - 4%
Contamination43 - 4.5%105 - 13%122 - 10%
Blood on tan cover10 - 1%14 - 2%26 - 2.5%
QNS to complete testing5 - .5%0 - 0%2 - 0.5%
Other18 - 2%38 - 5%112 - 10%
Total Unsatisfactory
Percent of All Samples
953 - 100%
1.4%
794 - 100%
1.2%
1173 - 100 %
1.6%