Martin Luther King, Jr. Day Holiday Schedule

Please note the following changes to the Wisconsin State Laboratory of Hygiene’s operations due to the observance of the Martin Luther King, Jr. Day holiday.

The table below lists the hours of operations for our Clinical Specimen Receiving departments. We will have staffing to accept clinical specimens at both our 2601 Agriculture Drive and our 465 Henry Mall facilities on Saturday, January 14th.

As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

 

DATE

2601 Agriculture Drive

Clinical Specimen Receiving

465 Henry Mall

Clinical Specimen Receiving

Saturday, January 14, 2017 6:30 AM – 2:30 PM 6:30 AM – Noon
Sunday, January 15, 2017 CLOSED CLOSED
Monday, January 16, 2017 CLOSED CLOSED

Worker Fatalities Increase in Wisconsin for 2015

According to the Bureau of Labor Statistics’ Census of Fatal Occupational Injuries, there were 104 Wisconsin workers who died due to injury in 2015. This number reflects an increase from 99 fatalities in 2014. Wisconsin’s overall fatality rate also increased from 3.5 to 3.6 deaths per 100,000. The number of workplace deaths in Wisconsin the past decade (2006-2015) range from 77 in 2008 to 114 in 2012, and average 98 fatalities annually.

The final count of occupational fatalities in the U.S. in 2015 was 4,836, according to national figures released last Friday. This was an increase from the revised total of 4,821 in 2014. The overall fatality rate decreased from 3.43 to 3.38 cases per 100,000 full time employees.

 Key findings for Wisconsin in 2015:

  • Work-related fatality rates decreased for agriculture, professional business services, and education and health services industries, and increased for construction, transportation, manufacturing, and wholesale and retail trade.
  • Transportation incidents caused the most fatalities, a 21% increase from the prior year.
  • Exposures to harmful substances or environments increased from 5 to 11 incidents.
  • Fatal injuries to females in 2015 decreased from 12 in 2014 to 4 in 2015.
  • Employees age 55 to 64 sustained the highest number of fatalities.

Industry

In 2015, 95 of the 104 work-related deaths in Wisconsin occurred within private industry. Public sector worker deaths increased from 5 deaths in 2014 to 9 in 2015. Agriculture, fishing, forestry, and hunting

fatality count decreased from 27 to 26. Fatalities in the professional and business services industry decreased from 13 to 7, while the trade, transportation, and utilities increased from 17 to 24. Manufacturing industry deaths rose from 11 in 2014 to 14 in 2015, while fatalities in the construction industry remained unchanged at 14.

Event

Transportation incidents comprised the highest number of fatal work injuries with 46 incidents, an increase from 39 incidents in 2014. Falls, slips, and trips increased slightly from 16 in 2014 to 17 last year, while fatal contact injuries decreased from 22 to 18. Violent events decreased from 15 in 2014 to 11 in 2015. Deaths due to exposure to harmful substance or environments increased from 5 to 11 incidents.

Worker Characteristics and Occupation

Of the 104 fatalities, 14 workers were in contractor status, and 39 were self-employed. The highest number of fatal work injuries occurred among age group 55 to 64 with 26 deaths, followed by age 45 to 54 with 22, and age 65 years or older with 19. Management occupations sustained the greatest number of fatal injuries in 2015 at 20 incidents, followed by transportation and material moving occupations with 19 deaths. Construction and extraction occupations sustained 13 fatalities, 11 deaths occurred among production workers and 10 among farming, fishing, and forestry occupations.

Background of Census of Fatal Occupational Injuries

The Census of Fatal Occupational Injuries, part of the BLS occupational safety and health statistics program, compiles a count of all fatal work injuries occurring in the United States during the calendar year. The program uses diverse state, federal, and independent data sources to identify, verify, and describe fatal work injuries. The Wisconsin State Laboratory of Hygiene (WSLH), a part of the University of Wisconsin-Madison, is the state’s public, environmental and occupational health laboratory. The WSLH’s Bureau of Labor Statistics/Occupational Safety and Health Statistics Program has a cooperative agreement with the U.S. Bureau of Labor Statistics to conduct the Census of Fatal Occupational Injuries in Wisconsin.

 

For more about Wisconsin Work-related fatalities, go to www.slh.wisc.edu/bls.

For more about U.S. Work-related fatalities, go to https://www.bls.gov/iif/news.htm

Toxicology Updates: OWI samples accepted and Dane County Roadside Oral Fluid Project Update

The Wisconsin State Laboratory of Hygiene Forensic Toxicology section provides alcohol and drug testing  for law enforcement agencies in Wisconsin for traffic safety and other motor vehicle matters (boats, ATVs and snowmobiles) in support of Wisconsin’s impaired driving laws.

 

OWI Samples

On Dec. 7, 2016, the toxicology section issued reminder guidance to law enforcement agencies that the WSLH will accept and test OWI blood samples for any OWI offense or crash, felony or otherwise. Memo

 

Dane County Roadside Oral Fluid Project

The WSLH Forensic Toxicology section is working with Dane County law enforcement agencies as part of the Dane County Roadside Oral Fluid Project, which focuses on suspected drugged driving. The WSLH recently published a summary of Phase 1 of the project.  Phase 2 is currently underway.

 

2016 Holiday Schedule

Please note the following changes to the Wisconsin State Laboratory of Hygiene’s operations due to the observance of the Christmas and New Year’s holidays.

The table below lists the hours of operations for our Clinical Specimen Receiving department. We will have staffing to accept clinical specimens at both our 2601 Agriculture Drive and our 465 Henry Mall facilities.

Testing will be performed in our Newborn Screening laboratory on Christmas Eve and New Year’s Eve. As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

 

DATE

2601 Agriculture Drive

Clinical Specimen Receiving

465 Henry Mall

Clinical Specimen Receiving

Saturday, December 24, 2016 – Christmas Eve 6:45 – 11:45 AM 6:30 AM – Noon
Sunday, December 25, 2016 – Christmas Day CLOSED CLOSED
Monday, December 26, 2016 – Observed Christmas Day CLOSED CLOSED
Saturday, December 31, 2016 – New Year’s Eve 6:45 – 11:45 AM 6:30 AM – Noon
Sunday, January 1, 2017 – New Year’s Day CLOSED CLOSED
Monday, January 2, 2017 – Observed New Year’s Day CLOSED CLOSED

 

Answering “Why” When Someone Suddenly Dies: Genetic Testing Pilot Project for Sudden Cardiac Deaths

DNA strandThe situation is terrifying. A seemingly healthy person suddenly collapses – unconscious – and tragically dies from cardiac arrest. Family members in their grief ask “Why?” and maybe even “Can it happen to us too?”

A pilot project between the University of Wisconsin Collaborative Genomics Core (UWCGC) and University of Wisconsin Hospital and Clinics (UWHC) Autopsy Services hopes to provide some answers.

The pilot project allows family members of people who pass away from suspected sudden cardiac deaths to have genetic testing performed on specimens from their deceased loved one, either as part of an autopsy at UWHC or just the testing alone. The test panel, performed by the UW Collaborative Genomics Core, is free of charge and looks for specific genetic markers related to sudden cardiac death.

Family members will receive the results of the testing from their designated healthcare provider. Genetic testing may identify inherited cardiac disease in 25-30% of these individuals. This provides the family an opportunity for closure, and also allows family members the option to be tested for the identified, and often treatable, genetic condition.

The goal is to identify gene variants related to sudden cardiac death in affected individuals to aid in diagnosis of at-risk family members who can then be connected with appropriate medical management.

“From one person who tragically dies, we can potentially help many people who might also be affected by hidden cardiac conditions,” said Jennifer Laffin, PhD FACMG, director of cytogenetics and molecular genetics within the UWCGC, director of UW Cytogenetics and Molecular Genetics at the Wisconsin State Laboratory of Hygiene (WSLH) and UW associate professor of Pediatrics. “We are hoping to significantly reduce sudden cardiac death in Wisconsin.”

The idea for the pilot project came from Kate Orland, MS CGC, a genetic counselor in the UW Department of Medicine’s Division of Cardiovascular Medicine. The team worked with Erin Brooks, MD, a UWHC pathologist and UW associate professor of Pathology and Laboratory Medicine, and WSLH Genetic Counselor Kimberly Anderson, MS CGC, to develop workflows and patient/provider tools to accomplish the testing.

“Although rare, sudden cardiac death in a young person (<40 years of age) does occur, leaving relatives in shock and eager to find an explanation,” Orland explained. “Genetic testing is sometimes the only tool available to determine the cause of death, particularly in the case of inherited arrhythmia conditions, which have little to no evidence on an autopsy.  Moreover, it is difficult to obtain insurance coverage for postmortem genetic testing.  The opportunity to offer testing to grieving families is not only a tremendous service; it can potentially provide critical risk assessment information for the living relatives, who could have a 50% chance of sharing the genetic variant.”

It’s expected that there will be about five cases of sudden cardiac death per year who will be tested as part of the pilot.

Family members also can have their loved one’s specimens banked at the WSLH DNA Bank for future testing.

“Although this testing won’t bring back their loved one, it can hopefully offer some insight into why they may have passed away and provide information to the surviving family members to help manage their health, if needed,” said Dr. Laffin.

Thanksgiving Holiday Hours

The Wisconsin State Laboratory of Hygiene will observe the following hours of operation for the Thanksgiving holiday:

 

2601 Agriculture Drive
DATE HOURS
Thursday, 11/24, Thanksgiving Day Closed
Friday, 11/25 6 AM-4:30 PM
Saturday, 11/26 6:30 AM-2:30 PM

 

465 Henry Mall
DATE HOURS
Thursday, 11/24, Thanksgiving Day Closed
Friday, 11/25 6 AM-4:30 PM
Saturday, 11/26 6:30 AM-12 PM (Noon)

 

Tracing the isotopic signature of lead – Is it bullets, water or paint?

Tracing the isotopic signature of lead (Pb) in both an adult who had bullet fragments embedded in his leg for 10 years and his young child who also had elevated blood lead levels (BLL) is the subject of a recent paper in Biological Trace Element Research.

The paper is the first resulting from isotopic analyses performed on the Multicollector Inductively Coupled Plasma Mass Spectrometer (MC-ICPMS) in the Wisconsin State Laboratory of Hygiene Trace Elements Clean Lab. The case is novel in that the MC-ICPMS was used for testing both clinical and environmental samples. The technology has been used for environmental testing for several years, but using it to test clinical specimens is still quite rare.

The article highlights the power of MC-ICPMS technology to determine isotopic signatures for environmental source tracking in public health.

Read the article here — http://link.springer.com/article/10.1007/s12011-016-0872-3

From the article …

“This study compared the high-precision isotopic fingerprints (<1 ‰ 2σ external precision) of Pb in the adult’s and child’s whole blood (WB) to the following possible Pb sources: a surgically extracted bullet fragment, household paint samples and tap water, and a Pb water-distribution pipe removed from servicing a house in the same neighborhood. Pb in the bullet and adult WB were nearly isotopically indistinguishable (matching within 0.05–0.56‰), indicating that bullet fragments embedded in soft tissue could be the cause of both acute and chronic elevated blood Pb levels. Among other sources investigated, no single source dominated the child’s exposure profile as reflected in the elevated BLL.”

 

Kate Smith, WSLH chemist and lead author on the article, analyzes samples using the Multicollector ICP-MS in the WSLH Trace Elements Clean Lab. The MC-ICPMS contains 9 Faraday detectors under high vacuum. Each detector can be tuned to measure the specific atomic mass of the individual isotopes of an element. With 9 detectors, the instrument is capable of measuring up to 9 different isotopes simultaneously. The instrument also contains a magnet that creates an electric field for separating the different masses of interest. Measuring the relative abundances of the isotopes of an element provides a “fingerprint” of the element in that sample. This can help determine where an element - and by association the sample - may have come from geographically, what environmental factors may have impacted the sample, or can be used as a tracer in clinical specimens, among other applications.

Kate Smith, WSLH chemist and lead author on the article, analyzes samples using the Multicollector ICP-MS in the WSLH Trace Elements Clean Lab. The MC-ICPMS contains 9 Faraday detectors under high vacuum. Each detector can be tuned to measure the specific atomic mass of the individual isotopes of an element. With 9 detectors, the instrument is capable of measuring up to 9 different isotopes simultaneously. The instrument also contains a magnet that creates an electric field for separating the different masses of interest. Measuring the relative abundances of the isotopes of an element provides a “fingerprint” of the element in that sample. This can help determine where an element – and by association the sample – may have come from geographically, what environmental factors may have impacted the sample, or can be used as a tracer in clinical specimens, among other applications.

Wisconsin Nonfatal Work Injuries Decline in 2015

diff-types-of-workers_shutterstock_241319935_webAccording to estimates from the U.S. Bureau of Labor Statistics’ Survey of Occupational Injuries and Illnesses (SOII), there were 78,800 total injuries and illnesses reported by Wisconsin employers in 2015, which occurred at a rate of 3.6 cases per 100 equivalent full-time workers. This is a decline from 4.0 in 2013 and 2014.  Nationwide, the total injury and illness case rate declined from 3.4 to 3.3 per 100 full-time workers.

Background:     

SOII is the largest work injury data survey conducted nationwide. The Wisconsin Bureau of Labor Statistics program collects data annually from a representative sample of 6,000 establishments, with a 97% survey response rate.

Key findings:*

  • Private industry incident rates fell from 3.9 to 3.6. State and local government total injury rate decreased from 4.7 cases per 100 full time workers to 4.2. (see chart 1).
  • All general industry sectors (excl. information) show a decline in total injury rates from the prior year. (see chart 2).
  • An equal proportion of worker injuries required time off or job restrictions to recuperate (39,600) and other recordable injuries which required medical treatment only (39,200).
  • Public sector sub-industries with the highest injury rates include: State nursing and residential care facilities (15.7), Local transit and ground passenger transportation (8.0), and Local heavy and civil engineering (6.6). (see chart 3).
  • Private sector sub-industries with the highest injury rates include: Couriers and messengers (9.7), Nonmetallic mineral manufacturing (7.9), Wood product manufacturing (7.1), Nursing and residential care facilities (6.9), Primary metal manufacturing (6.8), and Fabricated metal manufacturing (6.6).

*For charts and tables of Wisconsin data, go to www.slh.wisc.edu/bls. Data for case circumstances and worker characteristics will be available online mid-November.

The Wisconsin State Laboratory of Hygiene, a part of the University of Wisconsin-Madison, is the state’s public, environmental and occupational health laboratory. The WSLH’s Bureau of Labor Statistics/Occupational Safety and Health Statistics Unit have a cooperative agreement with the US Bureau of Labor Statistics to conduct their annual Survey of Occupational Injuries and Illnesses and Census of Fatal Occupational Injuries in Wisconsin.

Test. Fix. Save a Life. – Radon Awareness Week

shutterstock_243426319_lung-trees_webDid you know the 2nd leading cause of lung cancer is an odorless, colorless, radioactive gas?

It’s called radon and it can be found in up to 10% of the homes in Wisconsin at levels above the U.S. Environmental Protection Agency (EPA) guideline.

And the only way to find it is to test for it.

October 17-25 is Radon Awareness Week and homeowners interested in testing their homes for radon have many options.

The Wisconsin State Laboratory of Hygiene offers radon testing.

Homeowners can also contact Radon Information Centers or certified radon measurement contractors for testing or buy a test kit at a hardware store.

For more information on radon, health concerns, and a list certified radon reduction contractors, please see the WI Division of Health Services radon website at lowradon.org.

 

CDC Designates WSLH an Antibiotic Resistance Regional Lab

ar-lab-network-logoThe Centers for Disease Control and Prevention (CDC) has designated the WSLH Communicable Disease Division (WSLH CDD) an Antibiotic Resistance (AR) Regional Lab for the Midwest Region.

The WSLH is just 1 of 7 AR Regional Labs nationwide and will provide testing for Wisconsin, Michigan, Illinois, Indiana, Ohio and Kentucky.

 

According to the CDC, antibiotic resistance in the United States:

  • Sickens >2 million people per year
  • Kills at least 23,000 people each year + 15,000 each year from C. difficile
  • >$20B/year in healthcare costs
  • Threatens modern medicine – If we lose antibiotics, we lose the ability to treat patients with sepsis, cancer, provide organ transplants, and save victims of burns and trauma
  • Need to act now or even drugs of last resort will soon be ineffective

Part of the CDC’s AR Lab Network, the 7 AR Regional Labs are a critical component in building comprehensive laboratory capacity to detect and better characterize antibiotic-resistant pathogens. These labs will implement a regional approach to generate real-time, actionable data to prevent and combat AR threats.

According to the CDC’s AR Lab Network website:

“…labs designated as regional labs will be able to detect existing and emerging types of antibiotic resistance with gold-standard lab capacity, investigate emerging resistance faster and more effectively, and generate stronger data for improved infection control among patients to prevent and combat future resistance threats. … The regional labs will ensure more consistent and improved communication, coordination, and tracking at all levels—across healthcare facilities, state health departments, and CDC—every time. …”

All regional labs will perform core testing for their region, including:

  • Molecular testing to detect colonization of carbapenem-resistant Enterobacteriaceae (CRE)
  • Threat assessments, special threat assessments by request on new or known threats like MRSA, VRE, and VRSA
  • Isolate collection for use in CDC’s AR Isolate Bank and whole genome sequencing projects

In addition, the WSLH will perform testing for:

  • Reflex Culture pilot with Salmonella and Entertoxigenic E. coli
  • Antimicrobial susceptibility and serotyping of multidrug-resistant Streptococcus pneumoniae

WSLH CDD is also a CDC Reference Center for influenza surveillance, vaccine-preventable diseases, and foodborne/enteric diseases.

 

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