UW Pediatrics – Mei Wang Baker continues as a prolific genetic researcher and director of newborn screening

Dr. Mei Baker, UW Professor of Pediatrics and Director, Wisconsin State Laboratory of Hygiene Newborn Screening Laboratory, stands in the Allen Centennial Gardens on the University of Wisconsin-Madison campus.

The University of Wisconsin School of Medicine and Public Health Department of Pediatrics recently profiled Wisconsin State Laboratory of Hygiene Newborn Screening Director and Professor of Pediatrics Dr. Mei Baker.

In recounting Dr. Baker’s career at the University of Wisconsin-Madison, the article also traces the advancements of the Wisconsin Newborn Screening Laboratory. Article link

From the article
“Wisconsin’s newborn screening program is viewed as being at the forefront in the field,” Baker explained. “Our association with the university gives us a huge advantage, and I get a lot of support from the department. We are in a position to continue our work and to set an example. Our forward thinking allows us to obtain funding to do testing development.”

Baker plans to have potential screens ready when transformative treatment becomes available — to be proactive rather than reactive. “I am an optimist,” she stated.

 

UW School of Pharmacy – Playing Forensic Toxicology ‘Whack-a-Mole’

Heather Barkholtz, PhD, assistant professor in the University of Wisconsin-Madison School of Pharmacy and Wisconsin State Laboratory of Hygiene (WSLH) stands in the WSLH Forensic Toxicology laboratory where testing is performed for some of her research.

Heather Barkholtz, PhD, assistant professor in the University of Wisconsin-Madison School of Pharmacy and Wisconsin State Laboratory of Hygiene (WSLH) stands in the WSLH Forensic Toxicology laboratory where testing is performed for some of her research.

Assistant Professor Heather Barkholtz holds a unique joint appointment with the University of Wisconsin-Madison School of Pharmacy and the Wisconsin State Laboratory of Hygiene Forensic Toxicology section.

The UW-Madison Pharmacy School recently published an article detailing Dr. Barkholtz’s efforts “… to expand the limited research on drug impairment and develop better tools of detection for illegal substances. That would help both law enforcement and her colleagues at WSLH, the state’s public health laboratory that processes nearly 90 percent of samples from impaired drivers statewide.” Article link

 

From the article
“I’m the only faculty member studying forensic toxicology in the country who works alongside actual state practitioners,” she (Barkholtz) notes. “That means that we have great insight into what their pain points are and what they struggle with, and then that leads to our research. One of the things we’re working on is developing new ways to detect drugs of abuse in biological specimens, meaning blood or urine, and we’re trying to find methods that can detect a wide variety of different drugs in a short amount of time because we receive so many samples from across the state.”

Labor Day 2023 Holiday Hours

Please note the following changes to the Wisconsin State Laboratory of Hygiene’s operations for the Labor Day holiday.

As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

 

DATE

2601 Agriculture Drive

Clinical Specimen Receiving

Direct phone Saturdays: 608-224-4229

465 Henry Mall

Clinical Specimen Receiving

Direct phone Saturdays: 608-262-5817

Saturday, September 2, 2023 6:30 AM – 12:30 PM 7:00 AM – 12:00 Noon
Sunday, September 3, 2023 CLOSED CLOSED
Monday, September 4, 2023 CLOSED 7:00 AM-12:00 Noon
Newborn Screening Specimens Only

CDC Director Tours the WSLH

CDC Director Dr. Mandy Cohen toured the Wisconsin State Laboratory of Hygiene’s Agriculture Drive facility on August 16th. The WSLH is the first state public health laboratory Dr. Cohen has visited since becoming CDC Director in July.

While at the WSLH Dr. Cohen learned more about the WSLH’s role in emergency response, PFAS testing, wastewater surveillance for COVID-19 and other pathogens, and the WSLH’s expansive role in communicable disease testing, surveillance and outbreak response.

Dr. Cohen was visiting the state as part of the Wisconsin Department of Health Services’ efforts to encourage childhood immunizations.

Here are some scenes from her visit – (Photo credit: Jeremy Gehler, WI Department of Health Services)

 

Dr. Mandy Cohen listens as WSLH Chemical Emergency Response Manager Meshel Lange gives an overview of the program.

Dr. Mandy Cohen listens as WSLH Chemical Emergency Response Manager Meshel Lange (foreground) gives an overview of the program, which has 24/7 laboratory response capability and has helped support local public health and national public health response events related to both clinical and non-clinical chemical events.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Dr. Martin Shafer and Dr. Adelaide Roguet explain the WSLH’s wastewater surveillance program to Dr. Cohenand her aide Casey Garay.

Dr. Martin Shafer and Dr. Adelaide Roguet (yellow and blue shirt) explain the WSLH’s wastewater surveillance program to Dr. Cohen (right corner) and her aide Casey Garay. The CDC recently named the Wisconsin Wastewater Surveillance Program a National Center of Excellence for wastewater surveillance within the National Wastewater Surveillance System (NWSS). Wisconsin joins just three other CDC NWSS Centers of Excellence in the country.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Gathered in front of the WSLH’s Agriculture Drive facility on Madison’s east side are from left: Jan Klawitter, Camille Danielson, Dr. Martin Shafer and Dr. Alana Sterkel with the WSLH, WI DHS Deputy Secretary Deb Strandridge, CDC Director Dr. Mandy Cohen, WSLH Director Dr. Jamie Schauer, WSLH Associate Directors Dr. Errin Rider and Steve Strebel, and Jean Brody, state director of outreach for WI Senator Tammy Baldwin.

Gathered in front of the WSLH’s Agriculture Drive facility on Madison’s east side are from left: Jan Klawitter, Camille Danielson, Dr. Martin Shafer and Dr. Alana Sterkel with the WSLH, WI DHS Deputy Secretary Deb Strandridge, CDC Director Dr. Mandy Cohen, WSLH Director Dr. Jamie Schauer, WSLH Associate Directors Dr. Errin Rider and Steve Strebel, and Jean Brody, state director of outreach for U.S. Senator Tammy Baldwin.

WSLH Publishes 2022-2023 Annual Report

The Wisconsin State Laboratory of Hygiene’s 2022-2023 annual report – Transforming Challenges, Finding Solutions – is now available.

The report traces the continuum of the WSLH’s COVID-19 pandemic response activities – past, present and future – including genomic sequencing of variants, tracking disease through wastewater, and helping businesses protect their workers. The WSLH’s PFAS activities – both routine testing and research – is explored, as well as our partnerships around opioid and drug abuse surveillance, newborn screening, soil science, and much more.

Read the annual report

WSLH Brown Bag webinar: Shifty Characters – Cannabinoids and Opioids

Cannabinoids and opioids are two of the most commonly identified substance classes in Wisconsin’s impaired drivers. That said, these two classes of compounds are having profound impacts on our society, with shifting chemical structures and public perceptions.

UW-Madison Assistant Professor Heather Barkholtz gave a Brown Bag presentation for Wisconsin State Laboratory of Hygiene staff about the increasing prevalence of cannabinoids and opioids in society and knowledge gaps surrounding their use. Specifically, Dr. Barkholtz discussed the field of tetrahydrocannabinol (THC) isomers and efforts to better understand risks and protective factors associated with non-fatal overdoses.

Brown Bag recording

Wisconsin named National Center of Excellence for wastewater surveillance

wastewater samples in a 24-well tray are loaded into a scientific instrument for processing

Wastewater from participating treatment plants are set up and loaded onto an instrument at the Wisconsin State Laboratory of Hygiene for automated concentration of the SARS-CoV-2 virus for quantification.

The Centers for Disease Control and Prevention has named the Wisconsin Wastewater Surveillance Program a National Center of Excellence for wastewater surveillance within the National Wastewater Surveillance System (NWSS). Wisconsin joins just three other CDC NWSS Centers of Excellence in the country.

The Wisconsin Wastewater Surveillance Program is a partnership between the Wisconsin Department of Health Services, the Wisconsin State Laboratory of Hygiene at the University of Wisconsin–Madison, and the University of Wisconsin-Milwaukee School of Freshwater Sciences. The Wisconsin Wastewater Surveillance Program was an early pioneer during the COVID-19 pandemic in developing and applying wastewater-based surveillance for SARS-CoV-2 and is recognized as a national leader in wastewater-based monitoring of human pathogens.

Community-focused wastewater surveillance is a cost-effective tool for public health practice. It involves looking for the presence of pathogens that people shed in sewage, whether or not they have symptoms, and measuring the pathogen levels over time. Individual testing is not required, and it does not depend on individual access to a healthcare or testing location.

By screening for pathogens in untreated wastewater at a given central wastewater treatment facility, wastewater surveillance can help determine whether infections are increasing or decreasing in the community served by that facility and provide early warning about the spread or prevalence of disease. This can help public health agencies engage in prevention efforts where they are most needed and complement other data that public health agencies collect with respect to disease spread.

Read more at University of Wisconsin-Madison’s News

Milwaukee Journal-Sentinel: Everybody poops. Wisconsin is a national leader in using it to monitor public health.

4th of July 2023 Holiday Hours

Please note the following changes to the Wisconsin State Laboratory of Hygiene’s operations for the July 4th holiday.

As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

 

DATE

2601 Agriculture Drive

Clinical Specimen Receiving

Direct phone: 608-224-4229

465 Henry Mall

Clinical Specimen Receiving

Direct phone: 608-265-9188

Monday, July 3, 2023 6:00 AM – 4:30 PM 7:00 AM – 4:30 PM
Tuesday, July 4, 2023 CLOSED CLOSED
Wednesday, July 5, 2023 6:00 AM – 4:30 PM 7:00 AM – 4:30 PM