Former WSLH Director Dr. Stan Inhorn Passes Away

Former WSLH Director and Medical Director Dr. Stan Inhorn passed on February 19, 2025.

Dr. Inhorn was WSLH Assistant Director starting in 1960, becoming Director from 1966-1979. He then left to create and lead the UW Department of Pathology and Laboratory Medicine, eventually returning to the WSLH and retiring as WSLH Medical Director in the late 1990s.

Dr. Inhorn had a major impact on the WSLH and our role in the state and nation, as well as on healthcare in the United States.

Dr. Stan Inhorn obituary

An excerpt from his obituary recounting just some of his accomplishments –

“Stan moved to Madison in 1953 to pursue a five-year internship and residency in Pathology at the University of Wisconsin Hospital. Stan chose UW for his residency because the Wisconsin State Laboratory of Hygiene (WSLH) was the first state public health laboratory to be located on an academic campus. In the first year of his residency in the WSLH, Stan rotated through bacteriology, virology, serology, among other fields, and was also given space and supplies to start his own research. …

“At UW, Stan was appointed Assistant Professor of Pathology and Assistant Director of the WSLH in 1960. He became Director of the WSLH in 1966, a position he held until 1979, when he was asked by the UW Medical School to create a Department of Pathology and Laboratory Medicine. During his long career at WSLH, Stan pursued many different lines of medical research and public health intervention. He was involved in a large community program to promote the new Pap smear test for detecting cervical cancer. He created a Cytogenetics Lab at WSLH which identified the genetic trisomy 13, an important discovery in understanding congenital birth defects in children. With the American Cancer Society, he headed a demonstration project with a number of Wisconsin hospitals to determine the acceptance of offering low-cost mammography as a screening test for breast cancer.

“Starting in 1966, Stan played a major role in the implementation of Medicare, helping to develop the quality assurance (QA) practices to be required of all public health and clinical laboratories in this country. He chaired the Centers for Disease Control and Prevention (CDC) task force that developed the Proficiency Testing standards for the Clinical Laboratory Improvement Act of 1967 (CLIA-67). Stan was also a member of the Medical Laboratory Services Advisory Committee to CLIA. Stan, a past-chair of the Laboratory Section of the American Public Health Association, was selected to be editor of a book called Quality Assurance Practices for Health Laboratories. With 5 general chapters and 15 laboratory disciplines, this 1200-page volume was published in 1978. As laboratory practices and technology changed in the 1970s and 1980s, a revision of CLIA was made in 1988 (CLIA-88). Stan was appointed to the new CLIA-88 advisory committee. The Association of Public Health Laboratories (APHL) realized that a change was needed to connect laboratories to their users, including first responders, hospitals, health departments, etc. For his efforts at leading a new program called L-SIP to establish state-wide laboratory systems, Stan was awarded the Gold Standard Award by the APHL and later the organization’s Lifetime Achievement Award.”

Martin Luther King, Jr. Day 2025 Holiday Schedule

Please note the following changes to the Wisconsin State Laboratory of Hygiene’s operations due to the observance of the Martin Luther King, Jr. Day holiday.

The table below lists the hours of operations for our Clinical Specimen Receiving departments.

As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

 

DATE

2601 Agriculture Drive

Clinical Specimen Receiving

Direct phone: 608-224-4229

465 Henry Mall

Clinical Specimen Receiving

Direct phone: 608-262-5817

Saturday, January 18, 2025 6:30 AM – 12:30 PM 7:00 AM – Noon
Sunday, January 19, 2025 CLOSED CLOSED
Monday, January 20, 2025 CLOSED 7:00 AM – Noon

2024 Holiday Hours

Please note the following changes to the Wisconsin State Laboratory of Hygiene’s operations due to the observance of the Christmas and New Year’s holidays.

The table below lists the hours of operations for our Clinical Specimen Receiving department.

As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

 

DATE

2601 Agriculture Drive

Clinical Specimen Receiving

Direct Phone: 608-224-4229

465 Henry Mall

Clinical Specimen Receiving

Direct Phone for Saturdays/Holidays: 608-262-5817

Tuesday, December 24, 2024 – Christmas Eve 6:30 AM – 12:30 PM 7:00 AM – Noon
Wednesday, December 25, 2024 – Christmas Day CLOSED CLOSED
Tuesday, December 31, 2024 – New Year’s Eve 6:30 AM – 12:30 PM 7:00 AM – Noon
Wednesday, January 1, 2025 – New Year’s Day CLOSED CLOSED

Thanksgiving 2024 Holiday Hours

The Wisconsin State Laboratory of Hygiene will be closed on Thursday, November 28, 2024 for the Thanksgiving holiday.

Our Specimen Receiving departments will observe the following hours of operation for the Thanksgiving holiday:

 

2601 Agriculture Drive – Specimen Receiving
DATE HOURS
Thursday, 11/28, Thanksgiving Day CLOSED
Friday, 11/29 6 AM – 4:30 PM
Saturday, 11/30 6:30 AM – 12:30 PM

 

465 Henry Mall – Specimen Receiving
DATE HOURS
Thursday, 11/28, Thanksgiving Day CLOSED
Friday, 11/29 7 AM – 4:30 PM
Saturday, 11/30 7 AM – 12 PM (Noon)

As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

WSLH In the News – Cystic Fibrosis research, WI Partnership Program, and PFAS found in WI residents

The Wisconsin State Laboratory of Hygiene was featured in three recent stories published by the UW School of Medicine and Public Health (UWSMPH).

 

Pathbreaking cystic fibrosis research initiated in Wisconsin 40 years ago changed the course of diagnosis and treatment of children around the world

The WSLH Newborn Screening Program played a critical role in this groundbreaking research.

“The Wisconsin cystic fibrosis RCT project certainly laid the foundation for CF newborn screening in Wisconsin, in the nation, and beyond. CF newborn screening in Wisconsin continues to evolve,” she (WSLH Newborn Screening Director Dr. Mei Baker) explained. “With the adoption of next-generation sequencing technology, the newborn screening laboratory at the Wisconsin State Laboratory of Hygiene now can simultaneously detect 689 CF-causing variants. It is the most comprehensive panel at this time, and a relevant practice to the current discussion on genomic sequencing in newborn screening.”

UWSMPH story – https://www.pediatrics.wisc.edu/pathbreaking-cystic-fibrosis-research-initiated-in-wisconsin-40-years-ago-changed-the-course-of-diagnosis-and-treatment-of-children-around-the-world/

 

Wisconsin Partnership Program Turns 20 – Support for Medical and Public Health Education, Community Service and Research Helps Transform School

The latest issue of UWSMPH’s Quarterly magazine has a story on the 20th anniversary of the Wisconsin Partnership Program (WPP), which was started with a donation of half of the proceeds from the conversion of Blue Cross & Blue Shield United of Wisconsin from a non-profit to a for-profit corporation. The other half of the proceeds was donated to the Medical College of Wisconsin. The WPP has helped transform the UW Medical School into the UW School of Medicine and Public Health – the country’s first combined school of medicine and public health.

The WSLH gets a mention in the article as being key to this transformation.

“The initial Blue Cross/Blue Shield gift totaled more than $300 million to each school and had terms that are still followed today, including that 35 percent of its grants go to community health projects and 65 percent to research and education; requirements for oversight and accountability; and the call for then-dean Philip M. Farrell, MD, PhD (PG ’72), and Medical College of Wisconsin president Mike Bolger to jointly lead listening sessions to learn about health needs.

“We traveled the entire state, meeting with communities all the way up to Ashland on Lake Superior,” Farrell recalled. “We talked about the community-academic partnership theme. This was a natural for SMPH — our school was pursuing the Wisconsin Idea.”

A pediatrician and cystic fibrosis expert and now an emeritus dean, Farrell said it was his dream to create the country’s first combined school of medicine and public health.

“I realized that with our excellent Department of Population Health Sciences, world-class epidemiologists, and the Wisconsin State Laboratory of Hygiene on our campus, we had a strong core to become a school of medicine and public health,” he said. “Would we have been able to do it without the Blue Cross/Blue Shield money? Absolutely not.”

 

‘Forever chemicals’ show up in Wisconsin residents – Highest levels found in those who eat locally-caught fish

The WSLH Chemical Emergency Response (CER) section performed PFAS testing on serum samples from 605 adults as part of a collaborative UWSMPH, WSLH and WI Department of Health Services research study. The finding were published in Environmental Research – link below.

UWSMPH news releasehttps://www.med.wisc.edu/news/pfas-found-in-wisconsin-residents/

Determinants of per- and polyfluoroalkyl substances (PFAS) exposure among Wisconsin residents Environmental Research, Volume 254, 1 August 2024, 119131, https://doi.org/10.1016/j.envres.2024.119131

 

 

UW School of Pharmacy: Breaking Bad Chemistry

Heather Barkholtz, PhD, assistant professor in the University of Wisconsin-Madison School of Pharmacy and Wisconsin State Laboratory of Hygiene (WSLH) stands in the WSLH Forensic Toxicology laboratory where testing is performed for some of her research.

The UW School of Pharmacy profiles Assistant Professor Heather Barkholtz’s latest research in “Breaking Bad Chemistry”.

Barkholtz, who holds a joint appointment with the UW School of Pharmacy and the Wisconsin State Laboratory of Hygiene’s Forensic Toxicology section, received a National Institute of Justice grant to “…tease out the toxicological difference between mirror-image meth isomers.”

Barkholtz is also collaborating with School of Pharmacy and School of Medicine and Public Health faculty to research the intoxicating properties of various cannabinoids found in cannabis or marijuana products.

Read the story – https://pharmacy.wisc.edu/2024/09/05/breaking-bad-chemistry/

Labor Day 2024 Holiday Hours

Please note the following changes to the Wisconsin State Laboratory of Hygiene’s operations for the Labor Day holiday.

As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

 

DATE

2601 Agriculture Drive

Clinical Specimen Receiving

Direct phone Saturdays: 608-224-4229

465 Henry Mall

Clinical Specimen Receiving

Direct phone Saturdays: 608-262-5817

Saturday, August 31, 2024 6:30 AM – 12:30 PM 7:00 AM – 12:00 Noon
Sunday, September 1, 2024 CLOSED CLOSED
Monday, September 2, 2024 CLOSED 7:00 AM-12:00 Noon
Newborn Screening Specimens Only

UWSMPH: Data alerts community when sickness lurks

WSLH Microbiologists Devin Everett (left) and Evelyn Doolittle (right) operating the i5 Biomek liquid handler as part of the wastewater sequencing workflow.

Wisconsin State Laboratory of Hygiene wastewater surveillance data is just one contribution from University of Wisconsin School of Medicine and Public Health (UWSMPH) researchers to Public Health Madison-Dane County’s award-winning interactive respiratory illness dashboard.

More about the collaboration – https://www.med.wisc.edu/news/data-alerts-community-when-sickness-lurks/

4th of July 2024 Holiday Hours

Please note the following changes to the Wisconsin State Laboratory of Hygiene’s operations for the July 4th holiday.

As always, if you have an off-hours emergency, please call the WSLH Emergency Pager at 608-263-3280.

 

DATE

2601 Agriculture Drive

Clinical Specimen Receiving

Direct phone: 608-224-4229

465 Henry Mall

Clinical Specimen Receiving

Direct phone: 608-265-9188

Wednesday, July 3, 2024 6:00 AM – 4:30 PM 7:00 AM – 4:30 PM
Thursday, July 4, 2024 CLOSED CLOSED
Friday, July 5, 2024 6:00 AM – 4:30 PM 7:00 AM – 4:30 PM
Saturday, July 6, 2024 6:30 AM – 12:30 PM 7:00 AM – 12:00 Noon

New NADP Findings: East Palestine Train Derailment Caused Widespread Chemical Pollution

A new study published in the academic journal Environmental Research Letters, reveals that the environmental impact of the February 3, 2023, Norfolk Southern train accident in East Palestine, Ohio covered a very large geographical area. Inorganic pollutants released due to the accident were found in wet weather downfall (wet deposition) from the Midwest through the Northeast reaching as far as southern Canada and North Carolina. The findings are significant as many inorganic pollutants in rain and snow have chemical effects on aquatic flora and fauna. According to the paper, these pollutants spread over at least portions of 16 states and an area of 1.4 million square kilometers.

Researchers from the Wisconsin State Laboratory of Hygiene (WSLH) at the University of Wisconsin-Madison were able to estimate the spatial extent and chemical elements deposited resulting from the incident by using precipitation chemistry measurements routinely collected by the National Atmospheric Deposition Programs (NADP) National Trends Network (NTN), which makes routine wet weather measurements at 260 sites across North America.

The train accident and the subsequent fire resulted in the release of many different pollutants into the atmosphere over several days, which the NADP researchers were able to track in precipitation.

Lead researcher and coordinator of the National Atmospheric Deposition Program (NADP), which has been monitoring pollution deposited across North America in precipitation for over 40 years, David Gay, says: “Our measurements not only show the expected high chloride concentrations, but also the vast geographical area they covered. However, even more surprising are the unexpectedly high pH levels (more basic) and exceptionally elevated alkali and alkaline earth metals, exceeding the 99th percentiles of the last ten years of measurements. All of these pollutants are important in the environment because their accumulation has an impact on the Earth’s aquatic and terrestrial environments in many ways.”

“This study demonstrates the important role of a nationwide network for routine precipitation monitoring,” says Dr. Gay. “Our observations allowed us to determine the regional atmospheric impact from the accident and subsequent response activities.”

While the current NADP networks do not quantify organic compounds that might be more specific tracers of the train cargo, the documented widespread impacts on precipitation suggest a significant amount of chemical pollution falling to the earth’s surface as a result of the accident.

Journal article