Cytogenetics involves the study of human chromosomes in health and disease. Chromosome studies are an important laboratory diagnostic procedure in prenatal diagnosis, in certain patients with mental retardation and multiple birth defects, in patients with abnormal sexual development, and in some cases of infertility or multiple miscarriages. Cytogenetic analysis is also useful in the study and treatment of patients with malignancies and hematologic disorders. New techniques allow for increased resolution of chromosome banding patterns, permitting differentiation of a greater number of abnormalities.
In July, 2002, Waisman Center Cytogenetics and WSLH Cytogenetics merged to form UW Cytogenetic Services (UWCS). The UWCS laboratory is certified by CLIA (Clinical Laboratory Improvement Act), CAP (College of American Pathologists), and is COG (Childhood Oncology Group) approved. We provide chromosome analysis on a variety of specimens, including amniotic fluid, chorionic villus samples, tissue biopsies, products of conception, peripheral blood, bone marrow, lymph nodes, solid tumors, and pleural effusions. Cytogenetic studies are performed for prenatal diagnosis, to investigate infertility, to aid in identifying the cause of spontaneous abortions, to aid in determining the etiology of congenital anomalies, mental retardation, and learning disabilities, and to identify acquired chromosome abnormalities associated with neoplasia.
News From UW Cytogenetic Services
Webcast: Genetics Testing Services
Webcast: Detecting Genomic Imbalances in Stillborn Infants
UW Cytogenetics Director Gordana Raca receives grant to study genetic causes of eye malformations
Chromosomal Abnormalities in Cancer- a listing of neoplastic disorders including examples of associated chromosomal abnormalities
Related Sites - database searches, support/information on specific disorders, training in cytogenetics and genetic counseling
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Case Conference- a presentation of a recent interesting case, with the opportunity to analyze a metaphase spread before viewing the karyotype, description and discussion. (Replaces "Case of the Month"- no further updates)
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| Abnormalities that can be detected by cytogenetics: |
Some of the procedures that we perform: |
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Translocations
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Deletions
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Inversions
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Numerical aberrations
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Address:
UW Cytogenetic Services
465 Henry Mall, Room 419
Madison, WI 53706
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Email: cytogenetics@mail.slh.wisc.edu
Send us your comments, questions and suggestions. |
| Telephone: (608) 262-0402 |
FAX: (608) 265-7818 |
Questions about a specific disorder? training? -check out the Links to other sites also.
Site maintained by Eric B. Johnson ebjohnso@wisc.edu
