Inversions/Isochromosomes

 

Abnormal chromosome is on the right in each pair
Abnormality
(major breakpoint or breakpoint range)
Disorder

isochromosome 6p

i(6)(p10)

isochromosome 6p

i(6)(p10)

 i(6)(p10) retinoblastoma

i(7)(q10) Schwachman-Diamond, AML, MPN

isochromosome 12p

i(12)(p10)

isochromosome 12p

i(12)(p10)

 i(12)(p10) testicular germ cell tumor

isochromosome 17q

i(17)(q10)

isochromosome 17q

i(17)(q10)

 i(17)(q10) CML (secondary),  ALL,  AML,  primitive neuroectodermal tumor

inversion 3q

inv(3)(q21q26.2)

inversion 3q

inv(3)(q21q26.2)

  inv(3)(q21q26.2) AML,  MDS

inversion 16

inv(16)(p13.1q22)

inversion 16

inv(16)(p13.1q22)

 inv(16)(p13.1q22) AML
isochromosome Xp

idic(X)(q13)

 

isodicentric Xp

idic(X)(q13)

 idic(X)(q13) AML,  MDS

 

Deletions | Inversion/Isochromosome | Translocations 1 | Translocations 2

 

University of Wisconsin Cytogenetic Services